|
''Aspergillus nidulans'' (also called ''Emericella nidulans'' when referring to its sexual form, or teleomorph) is one of many species of filamentous fungi in the phylum Ascomycota. It has been an important research organism for studying eukaryotic cell biology for over 50 years, being used to study a wide range of subjects including recombination, DNA repair, mutation, cell cycle control, tubulin, chromatin, nucleokinesis, pathogenesis, metabolism, and experimental evolution. It is one of the few species in its genus able to form sexual spores through meiosis, allowing crossing of strains in the laboratory. ''A. nidulans'' is a homothallic fungus, meaning it is able to self-fertilize and form fruiting bodies in the absence of a mating partner. It has septate hyphae with a woolly colony texture and white mycelia. The green colour of wild-type colonies is due to pigmentation of the spores, while mutations in the pigmentation pathway can produce other spore colours. ==Genome== The ''A. nidulans'' genome was sequenced in a collaboration between Monsanto and the Broad Institute.〔(【引用サイトリンク】title=Aspergillus nidulans Project Information )〕 A sequence with 13-fold coverage was publicly released in March 2003;〔 analysis of the annotated genome was published in ''Nature'' in December 2005. It is 30 million base pairs in size and is predicted to contain around 9,500 protein-coding genes on eight chromosomes. Recently, several caspase-like proteases were isolated from ''A. nidulans'' samples under which programmed cell death had been induced. Findings such as these play a key role in determining the evolutionary conservation of the mitochondrion within the eukaryotic cell, and its role as an ancient proteobacterium capable of inducing cell death. 抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Aspergillus nidulans」の詳細全文を読む スポンサード リンク
|